Genetic Associations with Coronary Artery Disease

Genetic Associations with Coronary Artery Disease

Author: Ramakrishnan Veerabathiran

Publisher: LAP Lambert Academic Publishing

ISBN: 365934060X

Category:

Page: 180

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Coronary artery disease (CAD) is a narrowing of the small blood vessels that supply blood and oxygen to the heart. CAD is the most common form of heart disease in the Western world and is one of the leading causes of death in the United States. In addition to lifestyle and environmental factors which are major aetiologic determinants, there is considerable familial clustering of the disease indicating a genetic component in its causation. Although the total genetic contribution to CAD risk can be quantified, the determination of the size and number of contributing effects is impossible without identifying all CAD susceptibility genes. However, identifying clinically useful genetic markers for a complex disease like CAD has been challenging. Epidemiological evidence points to an approximate 50% genetic susceptibility to CAD. Many different genetic associations with CAD have been identified through family and population-based analysed, and genetic risk markers may be important for better defining individuals at risk for and cardiovascular events. In future advances in genomic research provide the valuable tools for understanding the genetic predisposition to coronary artery disease.
Report by the Task Force on Genetic Factors in Atherosclerotic Diseases
Language: en
Pages: 264
Authors: National Heart and Lung Institute. Task Force on Genetic Factors in Atherosclerotic Diseases, National Heart and Lung Institute. Division of Heart and Vascular Diseases
Categories: Arteriosclerosis
Type: BOOK - Published: 1976 - Publisher:

Books about Report by the Task Force on Genetic Factors in Atherosclerotic Diseases
Report
Language: en
Pages: 264
Authors: National Heart and Lung Institute. Task Force on Genetic Factors in Atherosclerotic Diseases
Categories: Arteriosclerosis
Type: BOOK - Published: 1976 - Publisher:

Books about Report
Cardiovascular Diseases
Language: en
Pages: 189
Authors: James J. Nora, Kåre Berg, Audrey Hart Nora
Categories: Travel
Type: BOOK - Published: 1991 - Publisher: Oxford University Press, USA

Knowledge of what causes cardiovascular diseases has progressed at a pace that challenges not only the student, but the physician and the research scientist. And while there is scientific merit in discovering the etiology of any disease, the ultimate goal is to apply what we learn to the treatment and
Genetic factors in coronary heart disease
Language: en
Pages: 463
Authors: U. Goldbourt, U. de Faire, K. Berg
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Incidence and mortality of atherosclerosis and coronary heart disease (CHD) vary considerably among races, populations and ethnic groups. Some individuals with low levels of risk factors succumb early to disease while many others with a high risk profile do not. CHD clusters in families and is manyfold increased in first
Report by the Task Force on Genetic Factors in Atherosclerotic Diseases
Language: en
Pages: 264
Authors: National Heart and Lung Institute. Task Force on Genetic Factors in Atherosclerotic Diseases, National Heart and Lung Institute. Division of Heart and Vascular Diseases
Categories: Arteriosclerosis
Type: BOOK - Published: 1976 - Publisher:

Books about Report by the Task Force on Genetic Factors in Atherosclerotic Diseases