Structural Biology in Drug Discovery

Structural Biology in Drug Discovery

Author: Jean-Paul Renaud

Publisher: John Wiley & Sons

ISBN: 9781118681015

Category: Medical

Page: 688

View: 205

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With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches, this book covers principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Presents the benefits, limitations, and potentiality of novel techniques in the field, like complex crystallization, X-ray diffraction, NMR, mass spectrometry, and computational chemistry Assesses macromolecular structures with experimental, analytical, and therapeutic approaches to reveal a successful, multidisciplinary perspective to drug development Includes detailed chapters on concepts, like protein dynamics, structure-based chemogenomics and polypharmacology, and fragment-based drug design Illustrates advances in biomolecular targeting using case studies and emerging examples: epigenetic proteins, HCV inhibitors, HIV-1 inhibitors, ribosomes, and antibodies
Structural Biology in Drug Discovery
Language: en
Pages: 688
Authors: Jean-Paul Renaud
Categories: Medical
Type: BOOK - Published: 2020-02-05 - Publisher: John Wiley & Sons

With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches, this book covers principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Presents the benefits, limitations, and potentiality of novel techniques in the field, like
Cytochrome P450
Language: en
Pages: 652
Authors: Paul R. Ortiz de Montellano
Categories: Medical
Type: BOOK - Published: 2013-11-11 - Publisher: Springer Science & Business Media

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Pages: 112
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Language: en
Pages: 320
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Categories: Biography & Autobiography
Type: BOOK - Published: 2019-07-11 - Publisher: Hachette UK

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