Introduction to Randomized Controlled Clinical Trials, Second Edition

Introduction to Randomized Controlled Clinical Trials, Second Edition

Author: John N.S. Matthews

Publisher: Chapman and Hall/CRC

ISBN: 1584886242

Category: Mathematics

Page: 304

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Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials provides a concise presentation of the principles applied in this area. It details the concepts behind randomization and methods for designing and analyzing trials and also includes information on meta-analysis and specialized designs, such as cross-over trials, cluster-randomized designs, and equivalence studies. This latest edition features new and revised references, examples, exercises, and a new chapter dedicated to binary outcomes and survival analysis. It also presents numerous examples taken from the medical literature, contains exercises at the end of each chapter, and offers solutions in an appendix. The author uses Minitab and R software throughout the text for implementing the methods that are presented. Comprehensive and accessible, Introduction to Randomized Controlled Clinical Trials is well-suited for those familiar with elementary statistical ideas and methods who want to further their knowledge of the subject.
Introduction to Randomized Controlled Clinical Trials, Second Edition
Language: en
Pages: 304
Authors: John N.S. Matthews
Categories: Mathematics
Type: BOOK - Published: 2006-06-26 - Publisher: Chapman and Hall/CRC

Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials
Randomised Controlled Clinical Trials
Language: en
Pages: 262
Authors: Christopher J. Bulpitt
Categories: Medical
Type: BOOK - Published: 2013-03-08 - Publisher: Springer

Bradford Hill has defined a clinical trial as "A carefully and ethically designed experiment with the aim of answering some precisely framed question" [1]. This definition specifies a careful design and requires the provision of adequate controls. Random allocation of treatments to subjects is important to ensure is entitled that
Randomised Controlled Clinical Trials
Language: en
Pages: 262
Authors: Christopher Bulpitt
Categories: Medical
Type: BOOK - Published: 1983 - Publisher: Springer

This is the first book on randomised controlled trials (RCTs) that attempts to deal with all aspects of trial design and execution. The text is primarily intended for research workers in the medical field, but scientists involved in any randomised trial should find the book of assistance. The first chapters
Randomized Controlled Trials
Language: en
Pages: 160
Authors: Alehandro R. Jadad, Murray W. Enkin
Categories: Medical
Type: BOOK - Published: 2008-04-15 - Publisher: John Wiley & Sons

Randomized controlled trials are one of the most powerful and revolutionary tools of research. This book is a convenient and accessible description of the underlying principles and practice of randomized controlled trials and their role in clinical decision-making. Structured in a jargon-free question-and-answer format, each chapter provides concise and understandable
Introduction to Randomized Controlled Clinical Trials
Language: en
Pages: 302
Authors: John N.S. Matthews
Categories: Mathematics
Type: BOOK - Published: 2006-06-26 - Publisher: CRC Press

Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials