The Polymerase Chain Reaction

The Polymerase Chain Reaction

Author: Kary B. Mullis

Publisher: Springer Science & Business Media

ISBN: 9781461202578

Category: Medical

Page: 458

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James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. "It has not escaped our notice," Francis wrote, "that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act ". . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before" and, moreover, " ...
The Polymerase Chain Reaction
Language: en
Pages: 458
Authors: Kary B. Mullis, Francois Ferre, Richard A. Gibbs
Categories: Medical
Type: BOOK - Published: 2012-02-02 - Publisher: Springer Science & Business Media

James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined
The Polymerase Chain Reaction
Language: en
Pages: 458
Authors: Kary B. Mullis, Francois Ferre, Richard A. Gibbs
Categories: Medical
Type: BOOK - Published: 1994-03-01 - Publisher: Birkhäuser

James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined
Polymerase Chain Reaction for Biomedical Applications
Language: en
Pages: 184
Authors: Ali Samadikuchaksaraei
Categories: Science
Type: BOOK - Published: 2016-12-14 - Publisher: BoD – Books on Demand

Do you want to know the details that should be taken into consideration in order to have accurate conventional and real-time PCR results? If so, this book is for you. Polymerase Chain Reaction for Biomedical Applications is a collection of chapters for both novice and experienced scientists and technologists aiming
The Polymerase Chain Reaction
Language: en
Pages: 80
Authors: Carman William Frederick
Categories: Science
Type: BOOK - Published: 1989 - Publisher:

Books about The Polymerase Chain Reaction
The polymerase chain reaction: one day workshop
Language: en
Pages:
Authors: Carman William Frederick
Categories: Science
Type: BOOK - Published: 1988 - Publisher:

Books about The polymerase chain reaction: one day workshop